Matemática e sustentabilidade no país da copa

O projeto intitulado Matemática e Sustentabilidade no País da Copa objetiva desenvolver conceitos matemáticos envolvendo as dimensões sociais, culturais, econômicas e ambientais, engendradas pela realização da Copa do Mundo no Brasil. A realização da primeira Copa Verde provocou grandes debates que instigaram a curiosidade e o interesse dos alunos com relação à Sustentabilidade. A problemática encontrada na Escola refere-se à necessidade de reflexão sobre hábitos e posturas dos estudantes e professores, com intervenção mediante estratégias de ações sustentáveis viáveis para a Escola, para a família e para a comunidade local. Foram utilizadas pesquisas de campo e bibliográfica, relacionando as dimensões macro, como cidades sedes da Copa e estádios, às micro, como a EEB Frei Crespim e a comunidade local. Relata-se, na análise de dados, a exploração e aplicação de conceitos matemáticos envolvendo campos numéricos, geometria plana e espacial, tratamento da informação e sistemas de medidas de modo significativo, contextualizado e interdisciplinar

D8.6 OPTIMAI commercialization and exploitation strategy

Deliverable D8.6 OPTIMAI commercialization and exploitation strategy 1 st version is the first version of the OPTIMAI Exploitation Plan. Exploitation aims at ensuring that OPTIMAI becomes sustainable well after the conclusion of the research project period so as to create impact. OPTIMAI intends to develop an industry environment that will optimize production, reducing production line scrap and production time, as well as improving the quality of the products through the use of a variety of technological solutions, such as Smart Instrumentation of sensors network at the shop floor, Metrology, Artificial Intelligence (AI), Digital Twins, Blockchain, and Decision Support via Augmented Reality (AR) interfaces. The innovative aspects: Decision Support Framework for Timely Notifications, Secure and adaptive multi-sensorial network and fog computing framework, Blockchain-enabled ecosystem for securing data exchange, Intelligent Marketplace for AI sharing and scrap re-use, Digital Twin for Simulation and Forecasting, Embedded Cybersecurity for IoT services, On-the-fly reconfiguration of production equipment allows businesses to reconsider quality management to eliminate faults, increase productivity, and reduce scrap. The OPTIMAI exploitation strategy has been drafted and it consists of three phases: Initial Phase, Mid Phase and Final Phase where different activities are carried out. The aim of the Initial phase (M1 to M12), reported in this deliverable, is to have an initial results' definition for OPTIMAI and the setup of the structures to be used during the project lifecycle. In this phase, also each partner's Individual Exploitation commitments and intentions are drafted, and a first analysis of the joint exploitation strategies is being presented. The next steps, leveraging on the outcomes of the preliminary market analysis, will be to update the Key Exploitable Results with a focus on their market value and business potential and to consolidate the IPR Assessment and set up a concrete Exploitation Plan. The result of the next period of activities will be reported in D8.7 OPTIMAI commercialization and exploitation strategy - 2nd version due at month 18 (June 2022

Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide

<p>Abstract</p> <p>Background</p> <p>Airway eosinophilia is considered a central event in the pathogenesis of asthma. The toxic components of eosinophils are thought to be important in inducing bronchial mucosal injury and dysfunction. Previous studies have suggested an interaction between nitric oxide (NO) and chemokines in modulating eosinophil functions, but this is still conflicting. In the present study, we have carried out functional assays (adhesion and degranulation) and flow cytometry analysis of adhesion molecules (VLA-4 and Mac-1 expression) to evaluate the interactions between NO and CC-chemokines (eotaxin and RANTES) in human eosinophils.</p> <p>Methods</p> <p>Eosinophils were purified using a percoll gradient followed by immunomagnetic cell separator. Cell adhesion and degranulation were evaluated by measuring eosinophil peroxidase (EPO) activity, whereas expression of Mac-1 and VLA-4 was detected using flow cytometry.</p> <p>Results</p> <p>At 4 h incubation, both eotaxin (100 ng/ml) and RANTES (1000 ng/ml) increased by 133% and 131% eosinophil adhesion, respectively. L-NAME alone (but not D-NAME) also increased the eosinophil adhesion, but the co-incubation of L-NAME with eotaxin or RANTES did not further affect the increased adhesion seen with chemokines alone. In addition, L-NAME alone (but not D-NAME) caused a significant cell degranulation, but it did not affect the CC-chemokine-induced cell degranulation. Incubation of eosinophils with eotaxin or RANTES, in absence or presence of L-NAME, did not affect the expression of VLA-4 and Mac-1 on eosinophil surface. Eotaxin and RANTES (100 ng/ml each) also failed to elevate the cyclic GMP levels above baseline in human eosinophils.</p> <p>Conclusion</p> <p>Eotaxin and RANTES increase the eosinophil adhesion to fibronectin-coated plates and promote cell degranulation by NO-independent mechanisms. The failure of CC-chemokines to affect VLA-4 and Mac-1 expression suggests that changes in integrin function (avidity or affinity) are rather involved in the enhanced adhesion.</p

Fragments scenic, untamed feelings

Orientador: Antonio Carlos Rodrigues AmorimDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de EducaçãoResumo: Essa dissertação, corpo-texto-imagem, é uma escrita potencializada pela força das imagens, que foge da interpretação para ser sentida. Visita cenas capturadas da peça teatral O Livro de Jó, encenada pela primeira vez no hospital Umberto Primo na capital paulista no início de 1995. Essas imagens, carregadas de significados e possibilidades, reverberam o contínuo movimento cênico a que se destinam e o desejo latente de se tornarem teatro pela força e pelo fluxo de sua intensidade. São imagens carregadas de dramaticidade e violência que também se aproximam da obra não menos perturbadora e pulsante do pintor irlandês Francis Bacon. Entre imagens do teatro e imagens do pintor, há uma corredeira de sensações que nos carrega, entre outros, aos franceses Artaud e Deleuze.Abstract: This dissertation, body-text-image, is a writing which is potentiated by the strength of the images, that runs away from its performing for being felt. It visits scenes caught by the play "The Book of Job ", staged for the first time at Umberto Primo Hospital São Paulo city in the early of 1995.These images, full of meanings and possibilities, reverberate around the continuous scenic movement for which they are intended, and the strong desire of becoming theater by the force and by the flow of its intensity. They are images loaded with drama and violence that also approaching the work, not least disruptive and pulsing to the Irish painter Francis Bacon. Between the images of the theater and images of the painter, there is a strong linking of sensations that lead us, among others, to the French Artaud and Deleuze.MestradoEducação, Conhecimento, Linguagem e ArteMestre em Educaçã

Cultural evolutionary design of adaptive wavelet filters based on lifting scheme for micro-instruments

An evolutionary procedure based on cultural algorithms for the optimal design of adaptive wavelet filters based on lifting scheme is proposed. Numerical results of characterization, based on statistical experiment design, as well as validation, based on the comparison with a genetic optimization algorithm, are presented. Experimental results of the validation on two case studies for reducing uncertainty arising from noise in on-field corrosion rate measurements are highlighted. (C) 2010 Elsevier Ltd. All rights reserved